Is Pepto-Bismol safe during pregnancy?
The famous pink stomach remedy contains a close cousin of aspirin.
Medically reviewed by Dr. Christopher Sterling, obstetrician ·
The short answer
Pepto-Bismol’s active ingredient, bismuth subsalicylate, is related to aspirin and is generally not recommended during pregnancy, especially in the second half. Ask a pharmacist about pregnancy-friendly options for heartburn, nausea or an upset stomach.
Why it matters
Bismuth subsalicylate breaks down into salicylate — the same family as aspirin. High salicylate exposure later in pregnancy raises similar concerns to NSAIDs, including effects on the baby’s heart and bleeding risk.
The same ingredient is found in some other diarrhoea and upset-stomach remedies (in the US, including some Kaopectate products).
What to do
- Check labels for “bismuth subsalicylate” or “salicylate”.
- For heartburn, ask your pharmacist about antacids suitable in pregnancy.
- For persistent diarrhoea or vomiting, contact your midwife or doctor — dehydration matters in pregnancy.
Common questions
What can I take for an upset stomach while pregnant?
It depends on the symptom. Many antacids are considered suitable for heartburn; for nausea or diarrhoea, ask a pharmacist or your midwife, and drink plenty of fluids.
Sources
Medically reviewed by Dr. Christopher Sterling, obstetrician, on against the sources above. Guidance can differ between countries — always follow the advice of your own midwife, doctor or pharmacist. Medical disclaimer.
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